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A strain-independent method to induce progressive and lethal pneumococcal pneumonia in neutropenic mice
BACKGROUND: Experimental models of pneumonia with penicillin non-susceptible Streptococcus pneumoniae (PNSSP) are hard to reproduce because the majority of strains with clinical relevance (like serotypes 6B, 9 V and 19 F) have low murine virulence. By optimization of culture and inoculum conditions...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474571/ https://www.ncbi.nlm.nih.gov/pubmed/25890037 http://dx.doi.org/10.1186/s12929-015-0124-4 |