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Modelling the conditional regulatory activity of methylated and bivalent promoters

BACKGROUND: Predictive modelling of gene expression is a powerful framework for the in silico exploration of transcriptional regulatory interactions through the integration of high-throughput -omics data. A major limitation of previous approaches is their inability to handle conditional interactions...

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Detalles Bibliográficos
Autores principales: Budden, David M., Hurley, Daniel G., Crampin, Edmund J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474576/
https://www.ncbi.nlm.nih.gov/pubmed/26097508
http://dx.doi.org/10.1186/s13072-015-0013-9