Tetraploid Embryonic Stem Cells Maintain Pluripotency and Differentiation Potency into Three Germ Layers

Polyploid amphibians and fishes occur naturally in nature, while polyploid mammals do not. For example, tetraploid mouse embryos normally develop into blastocysts, but exhibit abnormalities and die soon after implantation. Thus, polyploidization is thought to be harmful during early mammalian develo...

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Detalles Bibliográficos
Autores principales: Imai, Hiroyuki, Kano, Kiyoshi, Fujii, Wataru, Takasawa, Ken, Wakitani, Shoichi, Hiyama, Masato, Nishino, Koichiro, Kusakabe, Ken Takeshi, Kiso, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474668/
https://www.ncbi.nlm.nih.gov/pubmed/26091100
http://dx.doi.org/10.1371/journal.pone.0130585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474668/
https://www.ncbi.nlm.nih.gov/pubmed/26091100
http://dx.doi.org/10.1371/journal.pone.0130585

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