Regulation of DNA methylation dictates Cd4 gene expression during development of helper and cytotoxic T cell lineages

During development, progenitor cells with binary potential give rise to daughter cells that have distinct functions. Heritable epigenetic mechanisms then lock in gene expression programs that define lineage identity. Cd4 regulation in helper and cytotoxic T cells exemplifies this process, with enhan...

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Detalles Bibliográficos
Autores principales: Sellars, MacLean, Huh, Jun R., Day, Kenneth, Issuree, Priya D., Galan, Carolina, Gobeil, Stephane, Absher, Devin, Green, Michael R., Littman, Dan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474743/
https://www.ncbi.nlm.nih.gov/pubmed/26030024
http://dx.doi.org/10.1038/ni.3198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474743/
https://www.ncbi.nlm.nih.gov/pubmed/26030024
http://dx.doi.org/10.1038/ni.3198

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