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Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity

During the development of type 2 diabetes, endoplasmic reticulum (ER) stress leads to not only insulin resistance but also to pancreatic beta cell failure. Conversely, cell function under various stressed conditions can be restored by reducing ER stress by activating AMP-activated protein kinase (AM...

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Detalles Bibliográficos
Autores principales: Matsuda, Tomokazu, Takahashi, Hiroaki, Mieda, Yusuke, Shimizu, Shinobu, Kawamoto, Takeshi, Matsuura, Yuki, Takai, Tomoko, Suzuki, Emi, Kanno, Ayumi, Koyanagi-Kimura, Maki, Asahara, Shun-ichiro, Bartolome, Alberto, Yokoi, Norihide, Inoue, Hiroshi, Ogawa, Wataru, Seino, Susumu, Kido, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474801/
https://www.ncbi.nlm.nih.gov/pubmed/26091000
http://dx.doi.org/10.1371/journal.pone.0130757