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NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes

Neuroinflammation is the local reaction of the brain to infection, trauma, toxic molecules or protein aggregates. The brain resident macrophages, microglia, are able to trigger an appropriate response involving secretion of cytokines and chemokines, resulting in the activation of astrocytes and recr...

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Detalles Bibliográficos
Autores principales: Gustin, Audrey, Kirchmeyer, Mélanie, Koncina, Eric, Felten, Paul, Losciuto, Sophie, Heurtaux, Tony, Tardivel, Aubry, Heuschling, Paul, Dostert, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474809/
https://www.ncbi.nlm.nih.gov/pubmed/26091541
http://dx.doi.org/10.1371/journal.pone.0130624