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NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes
Neuroinflammation is the local reaction of the brain to infection, trauma, toxic molecules or protein aggregates. The brain resident macrophages, microglia, are able to trigger an appropriate response involving secretion of cytokines and chemokines, resulting in the activation of astrocytes and recr...
Autores principales: | Gustin, Audrey, Kirchmeyer, Mélanie, Koncina, Eric, Felten, Paul, Losciuto, Sophie, Heurtaux, Tony, Tardivel, Aubry, Heuschling, Paul, Dostert, Catherine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474809/ https://www.ncbi.nlm.nih.gov/pubmed/26091541 http://dx.doi.org/10.1371/journal.pone.0130624 |
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