Epigenetic Activity of Peroxisome Proliferator-Activated Receptor Gamma Agonists Increases the Anticancer Effect of Histone Deacetylase Inhibitors on Multiple Myeloma Cells

Epigenetic modifications play a major role in the development of multiple myeloma. We have previously reported that the PPARγ agonist pioglitazone (PIO) enhances, in-vitro, the cytotoxic effect of the Histone deacetylase inhibitor (HDACi), valproic acid (VPA), on multiple myeloma cells. Here, we des...

Descripción completa

Detalles Bibliográficos
Autores principales: Aouali, Nassera, Broukou, Angeliki, Bosseler, Manon, Keunen, Olivier, Schlesser, Vincent, Janji, Bassam, Palissot, Valerie, Stordeur, Philippe, Berchem, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474836/
https://www.ncbi.nlm.nih.gov/pubmed/26091518
http://dx.doi.org/10.1371/journal.pone.0130339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474836/
https://www.ncbi.nlm.nih.gov/pubmed/26091518
http://dx.doi.org/10.1371/journal.pone.0130339

Ejemplares similares