A Minimal Regulatory Network of Extrinsic and Intrinsic Factors Recovers Observed Patterns of CD4+ T Cell Differentiation and Plasticity

CD4+ T cells orchestrate the adaptive immune response in vertebrates. While both experimental and modeling work has been conducted to understand the molecular genetic mechanisms involved in CD4+ T cell responses and fate attainment, the dynamic role of intrinsic (produced by CD4+ T lymphocytes) vers...

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Detalles Bibliográficos
Autores principales: Martinez-Sanchez, Mariana Esther, Mendoza, Luis, Villarreal, Carlos, Alvarez-Buylla, Elena R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475012/
https://www.ncbi.nlm.nih.gov/pubmed/26090929
http://dx.doi.org/10.1371/journal.pcbi.1004324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475012/
https://www.ncbi.nlm.nih.gov/pubmed/26090929
http://dx.doi.org/10.1371/journal.pcbi.1004324

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