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In Vitro Induction of Endothelial Apoptosis of the Post-Hypoxic Blood-Brain Barrier by Isoflurane but Not by Sevoflurane and Midazolam

BACKGROUND: The effects of anesthetics on the injured brain continue to be the subject of controversial discussion. Since isoflurane has recently been shown to induce apoptosis of cerebral endothelial cells, this study compared different anesthetic compounds regarding their potential to induce cereb...

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Detalles Bibliográficos
Autores principales: Dittmar, Michael S., Petermichl, Walter, Lindner, Regina, Sinner, Barbara, Graf, Bernhard M., Schlachetzki, Felix, Gruber, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475016/
https://www.ncbi.nlm.nih.gov/pubmed/26091107
http://dx.doi.org/10.1371/journal.pone.0130408