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In Vitro Induction of Endothelial Apoptosis of the Post-Hypoxic Blood-Brain Barrier by Isoflurane but Not by Sevoflurane and Midazolam
BACKGROUND: The effects of anesthetics on the injured brain continue to be the subject of controversial discussion. Since isoflurane has recently been shown to induce apoptosis of cerebral endothelial cells, this study compared different anesthetic compounds regarding their potential to induce cereb...
Autores principales: | Dittmar, Michael S., Petermichl, Walter, Lindner, Regina, Sinner, Barbara, Graf, Bernhard M., Schlachetzki, Felix, Gruber, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475016/ https://www.ncbi.nlm.nih.gov/pubmed/26091107 http://dx.doi.org/10.1371/journal.pone.0130408 |
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