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BCAS2 Regulates Delta-Notch Signaling Activity through Delta Pre-mRNA Splicing in Drosophila Wing Development

Previously, we showed that BCAS2 is essential for Drosophila viability and functions in pre-mRNA splicing. In this study, we provide strong evidence that BCAS2 regulates the activity of Delta-Notch signaling via Delta pre-mRNA splicing. Depletion of dBCAS2 reduces Delta mRNA expression and leads to...

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Detalles Bibliográficos
Autores principales: Chou, Meng-Hsuan, Hsieh, Yi-Chen, Huang, Chu-Wei, Chen, Po-Han, Chan, Shih-Peng, Tsao, Yeou-Ping, Lee, Hsiu-Hsiang, Wu, June-Tai, Chen, Show-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475048/
https://www.ncbi.nlm.nih.gov/pubmed/26091239
http://dx.doi.org/10.1371/journal.pone.0130706