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BCAS2 Regulates Delta-Notch Signaling Activity through Delta Pre-mRNA Splicing in Drosophila Wing Development
Previously, we showed that BCAS2 is essential for Drosophila viability and functions in pre-mRNA splicing. In this study, we provide strong evidence that BCAS2 regulates the activity of Delta-Notch signaling via Delta pre-mRNA splicing. Depletion of dBCAS2 reduces Delta mRNA expression and leads to...
Autores principales: | Chou, Meng-Hsuan, Hsieh, Yi-Chen, Huang, Chu-Wei, Chen, Po-Han, Chan, Shih-Peng, Tsao, Yeou-Ping, Lee, Hsiu-Hsiang, Wu, June-Tai, Chen, Show-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475048/ https://www.ncbi.nlm.nih.gov/pubmed/26091239 http://dx.doi.org/10.1371/journal.pone.0130706 |
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