Avoiding the Enumeration of Infeasible Elementary Flux Modes by Including Transcriptional Regulatory Rules in the Enumeration Process Saves Computational Costs

Despite the significant progress made in recent years, the computation of the complete set of elementary flux modes of large or even genome-scale metabolic networks is still impossible. We introduce a novel approach to speed up the calculation of elementary flux modes by including transcriptional re...

Descripción completa

Detalles Bibliográficos
Autores principales: Jungreuthmayer, Christian, Ruckerbauer, David E., Gerstl, Matthias P., Hanscho, Michael, Zanghellini, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475075/
https://www.ncbi.nlm.nih.gov/pubmed/26091045
http://dx.doi.org/10.1371/journal.pone.0129840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475075/
https://www.ncbi.nlm.nih.gov/pubmed/26091045
http://dx.doi.org/10.1371/journal.pone.0129840

Ejemplares similares