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β(3)-Adrenoceptor-mediated relaxation of rat and human urinary bladder: roles of BK(Ca) channels and Rho kinase

Previous studies suggest that the large-conductance Ca(2+)-activated K(+) (BK(Ca)) channel and Rho-kinase play major roles in the control of urinary bladder tone. Here, we investigated their involvement in β-adrenoceptor (AR)-mediated relaxation of rat and human bladder. Concentration-response curve...

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Detalles Bibliográficos
Autores principales: Cernecka, Hana, Kersten, Kim, Maarsingh, Harm, Elzinga, Carolina R., de Jong, Igle Jan, Korstanje, Cees, Michel, Martin C., Schmidt, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475246/
https://www.ncbi.nlm.nih.gov/pubmed/25956403
http://dx.doi.org/10.1007/s00210-015-1128-z