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α-Melanocyte-stimulating-hormone (α-MSH) modulates human chondrocyte activation induced by proinflammatory cytokines

BACKGROUND: Alpha-melanocyte-stimulating-hormone (α-MSH) has marked anti-inflammatory potential. Proinflammatory cytokines are critical mediators of the disturbed cartilage homeostasis in osteoarthritis, inhibiting anabolic activities and increasing catabolic activities in chondrocytes. Since human...

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Detalles Bibliográficos
Autores principales: Capsoni, Franco, Ongari, Anna Maria, Lonati, Caterina, Accetta, Riccardo, Gatti, Stefano, Catania, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475285/
https://www.ncbi.nlm.nih.gov/pubmed/26093672
http://dx.doi.org/10.1186/s12891-015-0615-1