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The effect of simvastatin treatment on endothelial cell response to shear stress and tumor necrosis factor alpha stimulation

BACKGROUND: Statin drugs are one of the most commonly prescribed pharmaceuticals by physicians. By blocking the rate-limiting step in the cholesterol biosynthesis pathway, statins inhibit cholesterol synthesis, which benefits patient health. However, since many other important cellular processes are...

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Detalles Bibliográficos
Autores principales: Dick, Melissa, MacDonald, Katherine, Tardif, Jean-Claude, Leask, Richard L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475335/
https://www.ncbi.nlm.nih.gov/pubmed/26091905
http://dx.doi.org/10.1186/s12938-015-0057-x