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The effect of simvastatin treatment on endothelial cell response to shear stress and tumor necrosis factor alpha stimulation
BACKGROUND: Statin drugs are one of the most commonly prescribed pharmaceuticals by physicians. By blocking the rate-limiting step in the cholesterol biosynthesis pathway, statins inhibit cholesterol synthesis, which benefits patient health. However, since many other important cellular processes are...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475335/ https://www.ncbi.nlm.nih.gov/pubmed/26091905 http://dx.doi.org/10.1186/s12938-015-0057-x |