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β-PDGF Receptor Expressed by Hepatic Stellate Cells Regulates Fibrosis in Murine Liver Injury, but Not Carcinogenesis

BACKGROUND & AIMS: Rapid induction of β-PDGF receptor (β-PDGFR) is a core feature of hepatic stellate cell activation, but its cellular impact in vivo is not well characterized. We explored the contribution of β-PDGFR-mediated pathway activation to hepatic stellate cell responses in liver injury...

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Detalles Bibliográficos
Autores principales: Kocabayoglu, Peri, Lade, Abigale, Lee, Youngmin A., Dragomir, Ana-Cristina, Sun, Xiaochen, Fiel, M. Isabel, Thung, Swan, Aloman, Costica, Soriano, Philippe, Hoshida, Yujin, Friedman, Scott L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475471/
https://www.ncbi.nlm.nih.gov/pubmed/25678385
http://dx.doi.org/10.1016/j.jhep.2015.01.036