Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target

BACKGROUND: Neuroblastoma (NB) is an aggressive childhood malignancy in children up to 5 years of age. High-stage tumors frequently relapse even after aggressive multimodal treatment, and then show therapy resistance, typically resulting in patient death. New molecular-targeted compounds that effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Yco, Lisette P., Geerts, Dirk, Mocz, Gabor, Koster, Jan, Bachmann, André S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475614/
https://www.ncbi.nlm.nih.gov/pubmed/26093909
http://dx.doi.org/10.1186/s12885-015-1447-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475614/
https://www.ncbi.nlm.nih.gov/pubmed/26093909
http://dx.doi.org/10.1186/s12885-015-1447-y

Ejemplares similares