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PI3K mediated activation of GSK-3β reduces at-level primary afferent growth responses associated with excitotoxic spinal cord injury dysesthesias

BACKGROUND: Neuropathic pain and sensory abnormalities are a debilitating secondary consequence of spinal cord injury (SCI). Maladaptive structural plasticity is gaining recognition for its role in contributing to the development of post SCI pain syndromes. We previously demonstrated that excitotoxi...

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Detalles Bibliográficos
Autores principales: Bareiss, Sonja K, Dugan, Elizabeth, Brewer, Kori L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475622/
https://www.ncbi.nlm.nih.gov/pubmed/26093674
http://dx.doi.org/10.1186/s12990-015-0041-2