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Investigation of FOXP3 genetic variations at positions -2383 C/T and IVS9+459 T/C in southern Iranian patients with lung carcinoma

OBJECTIVE(S): FOXP3 gene is an X-linked gene that encodes FOXP3 protein, an essential transcription factor in CD4+CD25+FOXP3+ regulatory T (Treg) cells. We aimed, in the present study, to investigate the association of two FOXP3 polymorphisms, -2383 C/T (rs3761549) and IVS9+459 T/C (rs2280883), with...

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Detalles Bibliográficos
Autores principales: Fazelzadeh Haghighi, Maryam, Ghayumi, Mohammad Ali, Behzadnia, Farzane, Erfani, Nasrollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475654/
https://www.ncbi.nlm.nih.gov/pubmed/26124932