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Blockage of TGFβ-SMAD2 by demethylation-activated miR-148a is involved in caffeic acid-induced inhibition of cancer stem cell-like properties in vitro and in vivo

Current standard practices for treatment of cancers are less than satisfactory because of recurrence mediated by cancer stem cells (CSCs). Caffeic acid (CaA) is a novel anti-tumor agent that inhibits proliferation, migration, and invasion in human cancer cells. However, little is known about the fun...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Jiang, Fei, Chen, Lijun, Yang, Ye, Cao, Shuyuan, Ye, Yuting, Wang, Xingxing, Mu, Juan, Li, Zhong, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475776/
https://www.ncbi.nlm.nih.gov/pubmed/26106521
http://dx.doi.org/10.1016/j.fob.2015.05.009