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Stability-Indicating High-Performance Liquid Chromatographic Determination of Apixaban in the Presence of Degradation Products
A simple, robust, and stability-indicating reversed-phase high-performance liquid chromatographic (HPLC) method for the analysis of apixaban and its related substances has been successfully developed. Chromatography was performed on a 250 mm × 4.6 mm, 5 μm C(18) column with a gradient mixture of a p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Scientia Pharmaceutica
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475800/ https://www.ncbi.nlm.nih.gov/pubmed/26171323 http://dx.doi.org/10.3797/scipharm.1403-25 |