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Stability-Indicating High-Performance Liquid Chromatographic Determination of Apixaban in the Presence of Degradation Products

A simple, robust, and stability-indicating reversed-phase high-performance liquid chromatographic (HPLC) method for the analysis of apixaban and its related substances has been successfully developed. Chromatography was performed on a 250 mm × 4.6 mm, 5 μm C(18) column with a gradient mixture of a p...

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Detalles Bibliográficos
Autores principales: Prabhune, Swarup Suresh, Jaguste, Rajendra Shankar, Kondalkar, Prakash Laxman, Pradhan, Nitin Sharadchandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientia Pharmaceutica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475800/
https://www.ncbi.nlm.nih.gov/pubmed/26171323
http://dx.doi.org/10.3797/scipharm.1403-25