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GONAD: Genome-editing via Oviductal Nucleic Acids Delivery system: a novel microinjection independent genome engineering method in mice
Microinjection is considered the gold standard technique for delivery of nucleic acids (NAs; transgenes or genome editing tools such as CRISPR/Cas9 systems) into embryos, for creating genetically modified organisms. It requires sophisticated equipment as wel as well-trained and highly skilled person...
Autores principales: | Takahashi, Gou, Gurumurthy, Channabasavaiah B, Wada, Kenta, Miura, Hiromi, Sato, Masahiro, Ohtsuka, Masato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476150/ https://www.ncbi.nlm.nih.gov/pubmed/26096991 http://dx.doi.org/10.1038/srep11406 |
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