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Adaptive Evolution as a Predictor of Species-Specific Innate Immune Response

It has been proposed that positive selection may be associated with protein functional change. For example, human and macaque have different outcomes to HIV infection and it has been shown that residues under positive selection in the macaque TRIM5α receptor locate to the region known to influence s...

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Detalles Bibliográficos
Autores principales: Webb, Andrew E., Gerek, Z. Nevin, Morgan, Claire C., Walsh, Thomas A., Loscher, Christine E., Edwards, Scott V., O’Connell, Mary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476151/
https://www.ncbi.nlm.nih.gov/pubmed/25758009
http://dx.doi.org/10.1093/molbev/msv051