Association of aberrant DNA methylation in Apc(min/+) mice with the epithelial-mesenchymal transition and Wnt/β-catenin pathways: genome-wide analysis using MeDIP-seq

BACKGROUND: Aberrant DNA methylation at the 5-carbon on cytosine residues (5mC) in CpG dinucleotides is probably the most extensively characterized epigenetic modification in colon cancer. It has been suggested that the loss of adenomatous polyposis coli (APC) function initiates tumorigenesis and th...

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Detalles Bibliográficos
Autores principales: Guo, Yue, Lee, Jong Hun, Shu, Limin, Huang, Ying, Li, Wenji, Zhang, Chengyue, Yang, Anne Yuqing, Boyanapalli, Sarandeep SS, Perekatt, Ansu, Hart, Ronald P, Verzi, Michael, Kong, Ah-Ng Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476183/
https://www.ncbi.nlm.nih.gov/pubmed/26101583
http://dx.doi.org/10.1186/s13578-015-0013-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476183/
https://www.ncbi.nlm.nih.gov/pubmed/26101583
http://dx.doi.org/10.1186/s13578-015-0013-2

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