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ATP-dependent potassium channels are implicated in simvastatin pretreatment-induced inhibition of apoptotic cell death after renal ischemia/reperfusion injury

Background: Simvastatin is a widely used medication in cardiac care. Here we evaluate the role of ATP sensitive potassium (KATP) channels in simvastatin induced renal protection after renal ischemia/reperfusion (I/R) injury. Methods: A total of 81 male Wistar rats, were treated with simvastatin (10...

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Detalles Bibliográficos
Autores principales: Dowlatshahi, Kamran, Ajami, Marjan, Pazoki-Toroudi, Hamidreza, Hajimiresmaiel, Seyed Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iran University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476217/
https://www.ncbi.nlm.nih.gov/pubmed/26157709