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Genetic drift of human coronavirus OC43 spike gene during adaptive evolution

Coronaviruses (CoVs) continuously threaten human health. However, to date, the evolutionary mechanisms that govern CoV strain persistence in human populations have not been fully understood. In this study, we characterized the evolution of the major antigen-spike (S) gene in the most prevalent human...

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Detalles Bibliográficos
Autores principales: Ren, Lili, Zhang, Yue, Li, Jianguo, Xiao, Yan, Zhang, Jing, Wang, Ying, Chen, Lan, Paranhos-Baccalà, Gláucia, Wang, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476415/
https://www.ncbi.nlm.nih.gov/pubmed/26099036
http://dx.doi.org/10.1038/srep11451