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Improving prediction of secondary structure, local backbone angles, and solvent accessible surface area of proteins by iterative deep learning

Direct prediction of protein structure from sequence is a challenging problem. An effective approach is to break it up into independent sub-problems. These sub-problems such as prediction of protein secondary structure can then be solved independently. In a previous study, we found that an iterative...

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Detalles Bibliográficos
Autores principales: Heffernan, Rhys, Paliwal, Kuldip, Lyons, James, Dehzangi, Abdollah, Sharma, Alok, Wang, Jihua, Sattar, Abdul, Yang, Yuedong, Zhou, Yaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476419/
https://www.ncbi.nlm.nih.gov/pubmed/26098304
http://dx.doi.org/10.1038/srep11476