The mutant Moonwalker TRPC3 channel links calcium signaling to lipid metabolism in the developing cerebellum

The Moonwalker (Mwk) mouse is a model of dominantly inherited cerebellar ataxia caused by a gain-of-function mutation in the transient receptor potential (TRP) channel TRPC3. Here, we report impairments in dendritic growth and synapse formation early on during Purkinje cell development in the Mwk ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Dulneva, Anna, Lee, Sheena, Oliver, Peter L., Di Gleria, Katalin, Kessler, Benedikt M., Davies, Kay E., Becker, Esther B. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476454/
https://www.ncbi.nlm.nih.gov/pubmed/25908616
http://dx.doi.org/10.1093/hmg/ddv150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476454/
https://www.ncbi.nlm.nih.gov/pubmed/25908616
http://dx.doi.org/10.1093/hmg/ddv150

Ejemplares similares