The Early-Onset Myocardial Infarction Associated PHACTR1 Gene Regulates Skeletal and Cardiac Alpha-Actin Gene Expression

The phosphatase and actin regulator 1 (PHACTR1) locus is a very commonly identified hit in genome-wide association studies investigating coronary artery disease and myocardial infarction (MI). However, the function of PHACTR1 in the heart is still unknown. We characterized the mechanisms regulating...

Descripción completa

Detalles Bibliográficos
Autores principales: Kelloniemi, Annina, Szabo, Zoltan, Serpi, Raisa, Näpänkangas, Juha, Ohukainen, Pauli, Tenhunen, Olli, Kaikkonen, Leena, Koivisto, Elina, Bagyura, Zsolt, Kerkelä, Risto, Leosdottir, Margret, Hedner, Thomas, Melander, Olle, Ruskoaho, Heikki, Rysä, Jaana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476650/
https://www.ncbi.nlm.nih.gov/pubmed/26098115
http://dx.doi.org/10.1371/journal.pone.0130502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476650/
https://www.ncbi.nlm.nih.gov/pubmed/26098115
http://dx.doi.org/10.1371/journal.pone.0130502

Ejemplares similares