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The Early-Onset Myocardial Infarction Associated PHACTR1 Gene Regulates Skeletal and Cardiac Alpha-Actin Gene Expression
The phosphatase and actin regulator 1 (PHACTR1) locus is a very commonly identified hit in genome-wide association studies investigating coronary artery disease and myocardial infarction (MI). However, the function of PHACTR1 in the heart is still unknown. We characterized the mechanisms regulating...
Autores principales: | Kelloniemi, Annina, Szabo, Zoltan, Serpi, Raisa, Näpänkangas, Juha, Ohukainen, Pauli, Tenhunen, Olli, Kaikkonen, Leena, Koivisto, Elina, Bagyura, Zsolt, Kerkelä, Risto, Leosdottir, Margret, Hedner, Thomas, Melander, Olle, Ruskoaho, Heikki, Rysä, Jaana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476650/ https://www.ncbi.nlm.nih.gov/pubmed/26098115 http://dx.doi.org/10.1371/journal.pone.0130502 |
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