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Chenodeoxycholic Acid Reduces Hypoxia Inducible Factor-1α Protein and Its Target Genes
This study evaluated HIF-1α inhibitors under different hypoxic conditions, physiological hypoxia (5% O(2)) and severe hypoxia (0.1% O(2)). We found that chenodeoxy cholic acid (CDCA) reduced the amount of HIF-1α protein only under physiological hypoxia but not under severe hypoxia without decreasing...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476666/ https://www.ncbi.nlm.nih.gov/pubmed/26098428 http://dx.doi.org/10.1371/journal.pone.0130911 |