Suppression of MAPK Signaling and Reversal of mTOR-Dependent MDR1-Associated Multidrug Resistance by 21α-Methylmelianodiol in Lung Cancer Cells

Lung cancer is the leading cause of cancer-related deaths worldwide and remains the most prevalent. Interplay between PI3K/AMPK/AKT and MAPK pathways is a crucial effector in lung cancer growth and progression. These signals transduction protein kinases serve as good therapeutic targets for non-smal...

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Detalles Bibliográficos
Autores principales: Aldonza, Mark Borris Docdoc, Hong, Ji-Young, Bae, Song Yi, Song, Jayoung, Kim, Won Kyung, Oh, Jedo, Shin, Yoonho, Lee, Seung Ho, Lee, Sang Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476707/
https://www.ncbi.nlm.nih.gov/pubmed/26098947
http://dx.doi.org/10.1371/journal.pone.0127841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476707/
https://www.ncbi.nlm.nih.gov/pubmed/26098947
http://dx.doi.org/10.1371/journal.pone.0127841

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