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Alleviating Redox Imbalance Enhances 7-Dehydrocholesterol Production in Engineered Saccharomyces cerevisiae

Maintaining redox balance is critical for the production of heterologous secondary metabolites, whereas on various occasions the native cofactor balance does not match the needs in engineered microorganisms. In this study, 7-dehydrocholesterol (7-DHC, a crucial precursor of vitamin D(3)) biosynthesi...

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Detalles Bibliográficos
Autores principales: Su, Wan, Xiao, Wen-Hai, Wang, Ying, Liu, Duo, Zhou, Xiao, Yuan, Ying-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476719/
https://www.ncbi.nlm.nih.gov/pubmed/26098102
http://dx.doi.org/10.1371/journal.pone.0130840