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Alleviating Redox Imbalance Enhances 7-Dehydrocholesterol Production in Engineered Saccharomyces cerevisiae
Maintaining redox balance is critical for the production of heterologous secondary metabolites, whereas on various occasions the native cofactor balance does not match the needs in engineered microorganisms. In this study, 7-dehydrocholesterol (7-DHC, a crucial precursor of vitamin D(3)) biosynthesi...
Autores principales: | Su, Wan, Xiao, Wen-Hai, Wang, Ying, Liu, Duo, Zhou, Xiao, Yuan, Ying-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476719/ https://www.ncbi.nlm.nih.gov/pubmed/26098102 http://dx.doi.org/10.1371/journal.pone.0130840 |
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