Multi-Stage Tuberculosis Subunit Vaccine Candidate LT69 Provides High Protection against Mycobacterium tuberculosis Infection in Mice

Effective tuberculosis (TB) vaccine should target tubercle bacilli with various metabolic states and confer long-term protective immunity. In this study, we constructed a novel multi-stage TB subunit vaccine based on fusion protein ESAT6-Ag85B-MPT64(190-198)-Mtb8.4-HspX (LT69 for short) which combin...

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Detalles Bibliográficos
Autores principales: Niu, Hongxia, Peng, Jinxiu, Bai, Chunxiang, Liu, Xun, Hu, Lina, Luo, Yanping, Wang, Bingxiang, Zhang, Ying, Chen, Jianzhu, Yu, Hongjuan, Xian, Qiaoyang, Zhu, Bingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476732/
https://www.ncbi.nlm.nih.gov/pubmed/26098302
http://dx.doi.org/10.1371/journal.pone.0130641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476732/
https://www.ncbi.nlm.nih.gov/pubmed/26098302
http://dx.doi.org/10.1371/journal.pone.0130641

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