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Preferential Accumulation of (14)C-N-Glycolylneuraminic Acid over (14)C-N-Acetylneuraminic Acid in the Rat Brain after Tail Vein Injection
The two main molecular species of sialic acid existing in nature are N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc). Neu5Ac is abundant in mammalian brains and plays crucial roles in many neural functions. In contrast, Neu5Gc is present only at a trace level in vertebrate br...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476740/ https://www.ncbi.nlm.nih.gov/pubmed/26098915 http://dx.doi.org/10.1371/journal.pone.0131061 |