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Cardioprotection Resulting from Glucagon-Like Peptide-1 Administration Involves Shifting Metabolic Substrate Utilization to Increase Energy Efficiency in the Rat Heart

Previous studies have shown that glucagon-like peptide-1 (GLP-1) provides cardiovascular benefits independent of its role on peripheral glycemic control. However, the precise mechanism(s) by which GLP-1 treatment renders cardioprotection during myocardial ischemia remain unresolved. Here we examined...

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Detalles Bibliográficos
Autores principales: Aravindhan, Karpagam, Bao, Weike, Harpel, Mark R., Willette, Robert N., Lepore, John J., Jucker, Beat M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476748/
https://www.ncbi.nlm.nih.gov/pubmed/26098939
http://dx.doi.org/10.1371/journal.pone.0130894