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Cardioprotection Resulting from Glucagon-Like Peptide-1 Administration Involves Shifting Metabolic Substrate Utilization to Increase Energy Efficiency in the Rat Heart
Previous studies have shown that glucagon-like peptide-1 (GLP-1) provides cardiovascular benefits independent of its role on peripheral glycemic control. However, the precise mechanism(s) by which GLP-1 treatment renders cardioprotection during myocardial ischemia remain unresolved. Here we examined...
Autores principales: | Aravindhan, Karpagam, Bao, Weike, Harpel, Mark R., Willette, Robert N., Lepore, John J., Jucker, Beat M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476748/ https://www.ncbi.nlm.nih.gov/pubmed/26098939 http://dx.doi.org/10.1371/journal.pone.0130894 |
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