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Impaired Coronary and Renal Vascular Function in Spontaneously Type 2 Diabetic Leptin-Deficient Mice

BACKGROUND: Type 2 diabetes is associated with macro- and microvascular complications in man. Microvascular dysfunction affects both cardiac and renal function and is now recognized as a main driver of cardiovascular mortality and morbidity. However, progression of microvascular dysfunction in exper...

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Detalles Bibliográficos
Autores principales: Westergren, Helena U., Grönros, Julia, Heinonen, Suvi E., Miliotis, Tasso, Jennbacken, Karin, Sabirsh, Alan, Ericsson, Anette, Jönsson-Rylander, Ann-Cathrine, Svedlund, Sara, Gan, Li-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476758/
https://www.ncbi.nlm.nih.gov/pubmed/26098416
http://dx.doi.org/10.1371/journal.pone.0130648