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Reactive oxygen species induce Cox-2 expression via TAK1 activation in synovial fibroblast cells

Oxidative stress within the arthritis joint has been indicated to be involved in generating mediators for tissue degeneration and inflammation. COX-2 is a mediator in inflammatory action, pain and some catabolic reactions in inflamed tissues. Here, we demonstrated a direct relationship between oxida...

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Detalles Bibliográficos
Autores principales: Onodera, Yuta, Teramura, Takeshi, Takehara, Toshiyuki, Shigi, Kanae, Fukuda, Kanji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476901/
https://www.ncbi.nlm.nih.gov/pubmed/26110105
http://dx.doi.org/10.1016/j.fob.2015.06.001