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Reactive oxygen species induce Cox-2 expression via TAK1 activation in synovial fibroblast cells

Oxidative stress within the arthritis joint has been indicated to be involved in generating mediators for tissue degeneration and inflammation. COX-2 is a mediator in inflammatory action, pain and some catabolic reactions in inflamed tissues. Here, we demonstrated a direct relationship between oxida...

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Detalles Bibliográficos
Autores principales:	Onodera, Yuta, Teramura, Takeshi, Takehara, Toshiyuki, Shigi, Kanae, Fukuda, Kanji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476901/ https://www.ncbi.nlm.nih.gov/pubmed/26110105 http://dx.doi.org/10.1016/j.fob.2015.06.001

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