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PAX3 and ETS1 synergistically activate MET expression in melanoma cells

Melanoma is a highly aggressive disease that is difficult to treat due to rapid tumor growth, apoptotic resistance, and high metastatic potential. The MET tyrosine kinase receptor promotes many of these cellular processes, and while MET is often overexpressed in melanoma, the mechanism driving this...

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Detalles Bibliográficos
Autores principales: Kubic, Jennifer D., Little, Elizabeth C., Lui, Jason W., Iizuka, Takumi, Lang, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476961/
https://www.ncbi.nlm.nih.gov/pubmed/25531327
http://dx.doi.org/10.1038/onc.2014.420