Cargando…

Osteopontin Mediates an MZF1-TGF-β1-Dependent Transformation of Mesenchymal Stem Cells into Cancer Associated Fibroblasts in Breast Cancer

Interactions between tumor cells and cancer-associated fibroblasts (CAFs) in the tumor microenvironment (TMEN) significantly influence cancer growth and metastasis. Transforming growth factor-β (TGF-β) is known to be a critical mediator of the CAF phenotype, and osteopontin (OPN) expression in tumor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weber, Cynthia E., Kothari, Anai N., Wai, Philip Y., Li, Neill Y., Driver, Joseph, Zapf, Matthew A.C., Franzen, Carrie A., Gupta, Gopal N., Osipo, Clodio, Zlobin, Andrei, Syn, Wing Kin, Zhang, Jiwang, Kuo, Paul C., Mi, Zhiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476970/ https://www.ncbi.nlm.nih.gov/pubmed/25531323 http://dx.doi.org/10.1038/onc.2014.410

Ejemplares similares

Osteopontin—A Master Regulator of Epithelial-Mesenchymal Transition
por: Kothari, Anai N., et al.
Publicado: (2016)

The Mutational Landscape of the Oncogenic MZF1 SCAN Domain in Cancer
por: Nygaard, Mads, et al.
Publicado: (2016)

Therapeutic targeting of YY1/MZF1 axis by MZF1-uPEP inhibits aerobic glycolysis and neuroblastoma progression
por: Fang, Erhu, et al.
Publicado: (2020)

MZF1 and SCAND1 Reciprocally Regulate CDC37 Gene Expression in Prostate Cancer
por: Eguchi, Takanori, et al.
Publicado: (2019)

Zinc Finger Transcription Factor MZF1—A Specific Regulator of Cancer Invasion
por: Brix, Ditte Marie, et al.
Publicado: (2020)

Novel clinical therapeutics targeting the epithelial to mesenchymal transition
por: Kothari, Anai N, et al.
Publicado: (2014)

Epigallocatechin-3-Gallate Upregulates miR-221 to Inhibit Osteopontin-Dependent Hepatic Fibrosis
por: Arffa, M. L., et al.
Publicado: (2016)

p55PIK Transcriptionally Activated by MZF1 Promotes Colorectal Cancer Cell Proliferation
por: Deng, Yu, et al.
Publicado: (2013)

Notch-EGFR/HER2 Bidirectional Crosstalk in Breast Cancer
por: Baker, Andrew T., et al.
Publicado: (2014)

hMZF-2, the Elusive Transcription Factor
por: Chebly, Alain, et al.
Publicado: (2020)

MZF-1/Elk-1/PKCα is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma
por: Ye, Je-Chiuan, et al.
Publicado: (2017)

Inhibition of MZF1/c-MYC Axis by Cantharidin Impairs Cell Proliferation in Glioblastoma
por: Wang, Chie-Hong, et al.
Publicado: (2022)

Thirty-day hospital revisits after prostate brachytherapy: who is at risk?
por: Li, Belinda, et al.
Publicado: (2019)

Expression of osteopontin and osteonectin in breast cancer.
por: Kim, Y. W., et al.
Publicado: (1998)

The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK(+) T-cell lymphoma
por: Vishwamitra, Deeksha, et al.
Publicado: (2015)

MZF-1/Elk-1 Complex Binds to Protein Kinase Cα Promoter and Is Involved in Hepatocellular Carcinoma
por: Yue, Chia-Herng, et al.
Publicado: (2015)

MZF1 in the Dorsal Root Ganglia Contributes to the Development and Maintenance of Neuropathic Pain via Regulation of TRPV1
por: Xing, Fei, et al.
Publicado: (2019)

MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cells
por: Lee, Chia-Jen, et al.
Publicado: (2016)

MZF1 mediates oncogene-induced senescence by promoting the transcription of p16(INK4A)
por: Wu, Dan, et al.
Publicado: (2022)

Design and In Silico Validation of a Novel MZF-1-Based Multi-Epitope Vaccine to Combat Metastatic Triple Negative Breast Cancer
por: Krishnamoorthy, HemaNandini Rajendran, et al.
Publicado: (2023)

Correction: MZF-1/Elk-1 Complex Binds to Protein Kinase Cα Promoter and Is Involved in Hepatocellular Carcinoma
por: Yue, Chia-Herng, et al.
Publicado: (2015)

Therapeutic Targeting of MZF1‐AS1/PARP1/E2F1 Axis Inhibits Proline Synthesis and Neuroblastoma Progression
por: Fang, Erhu, et al.
Publicado: (2019)

Antisense oligonucleotides from the stage-specific myeloid zinc finger gene MZF-1 inhibit granulopoiesis in vitro
Publicado: (1991)

Gamma secretase inhibitors of Notch signaling
por: Olsauskas-Kuprys, Roma, et al.
Publicado: (2013)

Myeloid Zinc Finger 1 (Mzf1) Differentially Modulates Murine Cardiogenesis by Interacting with an Nkx2.5 Cardiac Enhancer
por: Doppler, Stefanie A., et al.
Publicado: (2014)

Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter
por: Briones-Orta, Marco Antonio, et al.
Publicado: (2017)

The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis
por: Xu, Kun, et al.
Publicado: (2016)

Up-Regulation of FOXM1 by E6 Oncoprotein through the MZF1/NKX2-1 Axis Is Required for Human Papillomavirus–Associated Tumorigenesis()()
por: Chen, Po-Ming, et al.
Publicado: (2014)

Maintaining Myofibroblastic-Like Cancer-Associated Fibroblasts by Cancer Stemness Signal Transduction Feedback Loop
por: Rogers, Michael P, et al.
Publicado: (2022)

Serum Interleukin‐8, Osteopontin, and Monocyte Chemoattractant Protein 1 Are Associated With Hepatic Fibrosis in Patients With Nonalcoholic Fatty Liver Disease
por: Glass, Oliver, et al.
Publicado: (2018)

UHRF1/DNMT1–MZF1 axis-modulated intragenic site-specific CpGI methylation confers divergent expression and opposing functions of PRSS3 isoforms in lung cancer
por: Lin, Shuye, et al.
Publicado: (2023)

Reply to: COVID-19 Vaccination in Patients who Develop COVID-19 After Cancer Surgery: Correspondence by Mungmunpuntipantip and Wiwanitkit
por: Verhagen, Nathaniel B., et al.
Publicado: (2023)

Osteopontin is a marker for cancer aggressiveness and patient survival
por: Weber, G F, et al.
Publicado: (2010)

Kinase GSK3β functions as a suppressor in colorectal carcinoma through the FTO‐mediated MZF1/c‐Myc axis
por: Zhang, Zeyan, et al.
Publicado: (2021)

Egr1/HSP70 Promoter-Driven Activation of Gene Expression for Synergistic Anti-Hepatoma Using PEI-MZF Nanoparticles and Radiation
por: Zhang, Jia, et al.
Publicado: (2022)

MZF1 Transcriptionally Activated MicroRNA-328-3p Suppresses the Malignancy of Stomach Adenocarcinoma via Inhibiting CD44
por: Qi, Zining, et al.
Publicado: (2022)

Osteopontin Is Upregulated in Human and Murine Acute Schistosomiasis Mansoni
por: Pereira, Thiago Almeida, et al.
Publicado: (2016)

Osteopontin regulates the growth and invasion of liver cancer cells via DTL
por: Liu, Zhiyong, et al.
Publicado: (2023)

MZF1 (Myeloid Zinc Finger 1) activates transcriptional activity of p53 and suppresses breast cancer cell proliferation via acetyltransferase PCAF (P300/CBP associated factor)
por: Li, Bowen, et al.
Publicado: (2022)

Axl Expression in Renal Mesangial Cells Is Regulated by Sp1, Ap1, MZF1, and Ep300, and the IL-6/miR-34a Pathway
por: Adams, David E., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ng9vvl20a9vcqqg9rru6cskqm6