Anti-repulsive Guidance Molecule C (RGMc) Antibodies Increases Serum Iron in Rats and Cynomolgus Monkeys by Hepcidin Downregulation

High levels of hepcidin, the main regulator of systemic iron metabolism, lead to various diseases. Targeting hepcidin and lowering its concentration is a possible form of intervention in order to treat these diseases. High turnover rate of hepcidin is a major drawback of therapies directly targeting...

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Detalles Bibliográficos
Autores principales: Böser, Preethne, Seemann, Dietmar, Liguori, Michael J., Fan, Leimin, Huang, Lili, Hafner, Mathias, Popp, Andreas, Mueller, Bernhard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476998/
https://www.ncbi.nlm.nih.gov/pubmed/25896304
http://dx.doi.org/10.1208/s12248-015-9770-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476998/
https://www.ncbi.nlm.nih.gov/pubmed/25896304
http://dx.doi.org/10.1208/s12248-015-9770-4

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