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AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia

Functional screening of expression libraries in vivo would offer the possibility of identifying novel biotherapeutics without a priori knowledge of their biochemical function. Here we describe a procedure for the functional selection of tissue-protective factors based on the in vivo delivery of arra...

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Detalles Bibliográficos
Autores principales: Ruozi, Giulia, Bortolotti, Francesca, Falcione, Antonella, Dal Ferro, Matteo, Ukovich, Laura, Macedo, Antero, Zentilin, Lorena, Filigheddu, Nicoletta, Cappellari, Gianluca Gortan, Baldini, Giovanna, Zweyer, Marina, Barazzoni, Rocco, Graziani, Andrea, Zacchigna, Serena, Giacca, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477044/
https://www.ncbi.nlm.nih.gov/pubmed/26066847
http://dx.doi.org/10.1038/ncomms8388