Protocatechuic Acid Prevents oxLDL-Induced Apoptosis by Activating JNK/Nrf2 Survival Signals in Macrophages

Protocatechuic acid (PCA), one of the main metabolites of complex polyphenols, exerts numerous biological activities including antiapoptotic, anti-inflammatory, and antiatherosclerotic effects. Oxidised LDL have atherogenic properties by damaging arterial wall cells and inducing p53-dependent apopto...

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Detalles Bibliográficos
Autores principales: Varì, Rosaria, Scazzocchio, Beatrice, Santangelo, Carmela, Filesi, Carmelina, Galvano, Fabio, D'Archivio, Massimo, Masella, Roberta, Giovannini, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477133/
https://www.ncbi.nlm.nih.gov/pubmed/26180584
http://dx.doi.org/10.1155/2015/351827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477133/
https://www.ncbi.nlm.nih.gov/pubmed/26180584
http://dx.doi.org/10.1155/2015/351827

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