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Protocatechuic Acid Prevents oxLDL-Induced Apoptosis by Activating JNK/Nrf2 Survival Signals in Macrophages
Protocatechuic acid (PCA), one of the main metabolites of complex polyphenols, exerts numerous biological activities including antiapoptotic, anti-inflammatory, and antiatherosclerotic effects. Oxidised LDL have atherogenic properties by damaging arterial wall cells and inducing p53-dependent apopto...
Autores principales: | Varì, Rosaria, Scazzocchio, Beatrice, Santangelo, Carmela, Filesi, Carmelina, Galvano, Fabio, D'Archivio, Massimo, Masella, Roberta, Giovannini, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477133/ https://www.ncbi.nlm.nih.gov/pubmed/26180584 http://dx.doi.org/10.1155/2015/351827 |
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