High-dose rifampicin kills persisters, shortens treatment duration, and reduces relapse rate in vitro and in vivo

Although high-dose rifampicin holds promise for improving tuberculosis control by potentially shortening treatment duration, these effects attributed to eradication of persistent bacteria are unclear. The presence of persistent Mycobacterium tuberculosis was examined using resuscitation promoting fa...

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Detalles Bibliográficos
Autores principales: Hu, Yanmin, Liu, Alexander, Ortega-Muro, Fatima, Alameda-Martin, Laura, Mitchison, Denis, Coates, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477163/
https://www.ncbi.nlm.nih.gov/pubmed/26157437
http://dx.doi.org/10.3389/fmicb.2015.00641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477163/
https://www.ncbi.nlm.nih.gov/pubmed/26157437
http://dx.doi.org/10.3389/fmicb.2015.00641

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